Trulicity, containing dulaglutide as the active ingredient, can have certain side effects. While not everyone experiences these effects, it is important to be aware of them. If you do encounter any of the following side effects while taking dulaglutide, seek medical attention promptly:

 

Less Common Side Effects:

  • Gaseous stomach pain
  • Indigestion
  • Severe nausea or vomiting
  • Stomach pain or fullness
  • Yellow eyes or skin

 

Incidence Unknown Side Effects:

  • Agitation
  • Change in urination
  • Chest tightness
  • Chills
  • Clay-colored stools
  • Cold sweats
  • Confusion
  • Cool, pale skin
  • Cough
  • Decreased urine output
  • Depression
  • Diarrhea
  • Difficulty with breathing or swallowing
  • Dizziness
  • Dry mouth
  • Fainting
  • Fast heartbeat
  • Fever
  • Headache
  • Hives, itching, skin rash
  • Hoarseness
  • Hostility
  • Increased hunger
  • Irritability
  • Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
  • Lethargy
  • Lightheadedness
  • Loss of appetite
  • Lump in the neck
  • Muscle twitching
  • Pains in the stomach, side, or abdomen, possibly radiating to the back
  • Rapid weight gain
  • Reddening of the skin, especially around the ears
  • Seizures
  • Severe constipation
  • Shakiness
  • Slurred speech
  • Sunken eyes
  • Swelling of the eyes or inside of the nose
  • Swelling of the face, ankles, or hands
  • Trouble breathing
  • Unpleasant breath odor
  • Unusual tiredness or weakness
  • Vomiting of blood
  • Wrinkled skin

 

Other Side Effects:

Some less common side effects of dulaglutide may occur, but they generally do not require medical attention. These side effects may diminish during treatment as your body adjusts to the medication. If any of the following side effects persist or become bothersome, consult your healthcare professional:

  • Acid or sour stomach
  • Belching
  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • Decreased appetite
  • General feeling of discomfort or illness
  • Heartburn
  • Lack or loss of strength
  • Stomach discomfort, upset, or pain